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MOPC-315

This murine plasmacytoma cell line has been used in a variety of studies involving cytokine biology and the immunotherapy of cancers. These tumor cells secrete large amounts of IL10 into the conditioned medium (Gorelik et al, 1994). They also ewxpress high amounts of IL6 and IL10 mRNAs, as determined by RT-PCR, but do not appear to express IL2, IL4, IL5, and IL12 mRNAs (Bost et al, 1995). The cells also produce TGF-beta (Weiskirch et al, 1994). The cells show significant expression of the apoptosis repressors ... ... ... ... ... Subscribe to continue reading! ... ...

 

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