MMP-10

[matrix metalloproteinase-10] Alternative designation are Stromelysin-2 (abbr. STMY2, SL-2, ST-2), Transin-2, and EC3.4.24.22. The human gene has been cloned by Sirum and Brinckerhoff (1989). MMP-10 is synthesized as an inactive proform that requires proteolytic processing for activation. Saunders et al (2005) have reported that a number of serine proteases can activate the proform of MMP-10, namely plasma kallikrein, trypsin, neutrophil elastase, cathepsin G, tryptase, and chymase.

Sirum and Brinckerhoff (1989) have reported expression in rheumatoid synovial ... ... ... ...
 
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Entry last modified: April 2006