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MAGED2

[Melanoma-associated antigen D2; melanoma antigen family D2] this gene is expressed ubiquitously in normal human tissues and in most, if not all, cell types (Lucas S et al, 1999; Langnaese et al, 2001).

MAGED2 has been reported to localize in both cytoplasm and nucleus, changing its localization during the cell cycle and under cell stress conditions (Pirlot C et al, 2016). The protein controls cell cycle progression and plays a role in the regulation of DNA damage response and the maintainance of genomic stability (Trussart C et al, 2018).


Role in apoptosis

Tseng H-Y et al (2012) have reported a role in cell death by apoptosis ... ... ... ...
 
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Entry last modified: February 2024



 
 
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