Leukemia-derived growth factor
this term has multiple meanings
(-1-) abbr. LDGF (a term with multiple meanings).
This factor is produced by the human acute lymphoblastoid T-cell leukemia cell line MOLT-4 and some other malignant T-lymphoid cells. A factor with an identical biological behavior is secreted also by murine T-cell lymphomas.
This factor of 5-15 kDa is not identical with IL1, IL2, IL3, GM-CSF, EGF, TGF-alpha, TGF-beta. It stimulates the proliferation of the producer cells (autocrine
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