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Kit225

A human T-cell line established from a patient with T-cell chronic lymphocytic leukemia. The cells express the markers CD3, CD4 but not CD8. The cells are not infected with HTLV I or II (Hori et al, 1987). Kit225 cells express a large amount of IL2 receptors constitutively, and their growth is absolutely dependent on IL2 (see also: Factor-dependent cell lines). No other stimuli, such as lectins or antigens, are required for maintaining the responsiveness to IL2 (Hori et al, 1987).

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