KW-2228
marketed under the names Marograstim and Nartograstim. A recombinant, N-terminally modified form of human G-CSF in which Thr1, Leu3, Gly4, Pro5, and Cys17 are substituted with Ala, Thr, Tyr, Arg, and Ser, respectively. The protein is produced in Escherichia coli.
KW-2228 is more stable than the genuine recombinant factor (see also: Recombinant cytokines, Muteins). It displays a high specific activity, has an increased plasma half-life and improved pharmacokinetic behavior. The factor supports granulopoiesis in the mouse much better than the parent factor. It stimulates the growth of CFU-G in soft agar (see also:
...
...
...
...
... Subscribe to continue reading!
... ...
Content view restricted !
COPE - with 54500+ entries the most comprehensive cell-to-cell communication knowledge base
Extensive In-depth and In Context Information covering terminology,
nomenclature, concepts, strategies & complexities of cellular communication, including
Acute phase proteins |
Angiogenesis |
Antimicrobial & host defense peptides |
Apoptosis & other forms of cell death |
CD antigens |
Cell lines |
Cell reprogramming |
Chemokines |
Cryptides |
Cytokines & Growth factors |
CytokineTopics |
Eukaryotic cell types & expression profiles |
Hematopoiesis |
Hormones |
Inflamation & inflammatory mediators |
Innate Immunity |
Metalloproteinases |
Microvesicles / Microparticles |
Moonlighting proteins & cryptides |
Neuropeptides |
Non-coding RNAs |
Pathogenicity & Virulence Factors |
Pattern recognition receptors |
Peptide sequences |
Protein domains |
Regulatory peptide factors |
Viroceptors |
Virokines and more.
Full COPEing for subscribers:
Access to Alphabet bar, Freetext search, Leafing/browsing functions, Internal Backlinking,
Topic-specific introductions, Topic-specific integrated subdictionaries, Scientific references with PubMed links
with a 15 USD/month subscription at
Cells-Talk.com
See example pages at the bottom of the Cells-Talk.com home page
THE SMART ONES COPE
The others just sisyphos around
|
ENTRY LAST MODIFIED: January 2002
| # |
A |
B |
C |
D |
E |
F |
G |
H |
I |
J |
K |
L |
M |
N |
O |
P |
Q |
R |
S |
T |
U |
V |
W |
X |
Y |
Z |
U L T R A P O S S E
N E M O O B L I G A T U R
cope.cgi Version 1.41 [08.12.2020]. (c) JI. Powered by Perl 5.032001. key=29319