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K9CATH

This peptide, RLKELITTGGQKIGEKIRRIGQRIKDFFKNLQPREEKS, is a canine antimicrobial protein belonging to the family of cathelicidins (Sang et al, 2007). The 38 amino acid mature K9CATH peptide is derived from a larger precursor and is present in neutrophil granules. Synthetic K9CATH displays broad antimicrobial activity against Gram-positive bacteria (Listeria monocytogenes, and Staphylococcus aureus), Gram-negative bacteria (Escherichia coli, Klebsiella pneumoniae, Salmonella typhimurium, Pseudomonas aeruginosa, Proteus mirabilis), and yeast (Candida albicans). K9CATH is active also against Ureaplasma canigenitalium and Ureaplasma urealyticum. Similar to ovine SMAP-29 ... ... ... ... ... Subscribe to continue reading! ... ...

 

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