invasin(pstb) |
Invasion-inhibiting factor-2 |
GFE-2 |
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[invasin]
This general term refers to proteins expressed on the cell surface of various pathogens. Invasins constitute a large heterogenous group of proteins (Tsai et al, 2010) that facilitate entry of the pathogen into host cells through specific interactions with receptors expressed on many different host cell types. Thus, like intimin, they fulfill the functions of bacterial adhesins. This interaction is critical for infection and virulence and also permits internalization of pathogens into non-phagocytic host cells (Cambronne and Schneewind, 2005; Niemann et al, 2004).
For other relevant entries see also the Pathogenicity/Virulence Factors Dictionary section of this encyclopedia.
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