Immunoregulin TP 1 |
immunosubversion |
A11 amacrine cells |
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This decapeptide, SLTCLVKGFY (Ser-Leu-Thr-Cys-Leu-Val-Lys-Gly-Phe-Tyr) corresponds to amino acids 364-373 of the CH3 domain of the human immunoglobulin G1 Eu heavy chain (IgG1 heavy chain (364-373); Immunoglobulin G1 heavy chain (364-373); IgG1 Eu heavy chain (364-373)) (Zav’yalov et al, 1996).
The peptide increases, at very low concentrations, the proliferation of human T-cells induced in vitro by concanavalin A (Navolotskaya et al, 2001, 2002), stimulates the growth of human T-lymphoblast cell lines Jurkat
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