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IL20L

[IL20-like; interleukin-20-like] The gene encoding this protein (156 amino acids) related to IL20 has been identified in the rainbow trout (Oncorhynchus mykiss) (Wang T et al, 2010). Fish IL20L proteins form an independent clade but cluster with the group containing the IL19, IL20 and IL24. IL20L is expressed in immune related tissues and in the brain. Macrophages express IL20L and expression is modulated by pro-inflammatory cytokines, signaling pathway activators, microbial mimics, and the immuno-suppressor dexamethasone.

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