ICSBP

[interferon consensus sequence binding protein] This is the same as ICSBP-1 [interferon consensus sequence binding protein-1]. The new name is IRF8 [interferon regulatory factor-8]. This protein belongs to the family of interferon regulatory factors (see also: IRF1, IRF2), transcription factors that regulate the expression of IFN-alpha, IFN-beta and genes regulated by these interferons by binding to a regulatory domain known ISRE. The gene for ICSBP has been cloned by Weisz et al (1992). The gene appears to be expressed exclusively in ... ... ... ...
 
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Entry last modified: January 2003