Hypotensins

This term has been used for a group of factors from the Brazilian scorpion Tityus serrulatus venom with hypotensive activity. They potentiate the activity of Bradykinin but do not inhibit the activity of ACE [angiotensin-converting enzyme; angiotensin-1 converting enzyme] (CD143).

TsHpt1 [Tityus serrulatus Hypotensin-1] [Hypotensin-1] has the sequence AEIDFSGIPEDIIKQIKETNAKPPA. It is subject to extensive proteolysis and yields many fragments of unknown function (Verano-Braga et al, 2013). TsHpt3 [Tityus serrulatus Hypotensin-3] [Hypotensin-3] lacks the C-terminal amino acid of Hypotensin-1 ... ... ... ...
 
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Entry last modified: December 2016