Hemopoietin-2 |
Hemopressin-alpha |
frizzled family receptor 2 |
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abbr. Hp; in some publications Hemopressin is being referred to as Hp(1-9). This peptide of 9 amino acids peptide [PVNFKFLSH] is derived from the alpha-chain of hemoglobin and was identified originally as a substrate of the metalloproteinase Thimet oligopeptidase (Rioli et al, 2003; Dale et al, 2005). It is metabolized in vivo and in vitro by Thimet oligopeptidase, neurolysin, and angiotensin-converting enzyme (Dale et al, 2005). The peptide corresponds to rat hemoglobin-alpha-1(95-103). The sequence of the human or mouse
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