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HPF-1

[Hepatocyte proliferation factor-1] HPF-1 (26-31 kDa) and HPF-2 [Hepatocyte proliferation factor-2] (71-90 kDa) are biochemically uncharacterized factors found in the condition medium of neonatal pig liver (Hiyoshi et al, 2002). HPF-1 stimulates DNA synthesis of primary rat hepatocytes, but suppresses that of HepG2 cells. HPF-2 stimulates DNA synthesis of primary rat hepatocytes but does not suppress that of HepG2 cells.

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