HPC-1 |
HPESCRG1 |
chromosome 20 open reading frame 103 |
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[hemopoietic progenitor cell antigen 1; human progenitor cell antigen 1] HPCA1 is expressed selectively on human hematopoietic progenitor cells. Nearly all the (day 14) lineage-restricted and multipotential colony forming cells analysed in methylcellulose cultures in the presence of added growth factors express HPCA-1 determinants and HLA-DR. Other tissues are nonreactive with the exception of capillary endothelia and basement membrane in some sites (Watt et al, 1987). The adherent cells expressing HPCA1 represent approximately 1 % of normal human bone marro suspensions and include colony-forming units (CFU) of granulocytes and macrophages (
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