H1299.2 peptide |
H2009.1 peptide |
NUAK1 |
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This targeting peptide with the sequence LQWRRDDNVHNFGVWARYRL has been identified by phage display library screening as a peptide that is preferentially internalized by H1299 non-small cell lung cancer cells via endocytosis (Umlauf et al (2014). Umlauf et al (2015) have used liposomes coated with this targeting peptide and containing H250, an immunogenic human leukocyte antigen class 1 restricted peptide. Treatment with these liposomes, which facilitate the presentation of the H250 peptide, significantly reduces tumor growth using an aggressive LLC1 model in vaccinated C57BL/6 mice.
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