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gray platelet syndrome |
Multilineage hemopoietic growth factor |
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a 250 kDa intracellular protein (1,780 amino acids), originally identified as a cytoplasmic antigen recognized by myasthenia gravis sera (Gordon et al, 1992; Sasaki et al, 2001). Autoantibodies to gravin are highly specific for myasthenia gravis. (Nauert et al, 1997; Sasaki et al, 2001). The protein is known also as human AKAP250 [A-kinase anchor protein 250 kDa; cAMP-dependent protein kinase-anchor protein 250]), AKAP12 [A-kinase anchor protein 12; approved gene symbol], or SSeCKS [src-suppressed C kinase substrate], a rat ortholog, the expression of which in astrocytes
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