GnIH

[gonadotropin-inhibitory hormone] GnIH (SIKPSAYLPLRFamide; Ser-Ile-Lys-Pro-Ser-Ala-Tyr-Leu-Pro-Leu-Arg-Phe) is a hypothalamic dodecapeptide hormone that inhibits gonadotropin release. It has been identified first in quail (Tsutsui et al, 2000; Satake H et al, 2001). The peptide belongs to a larger class of the so-called RFamide-related peptide (RFRP) familiy characterized by the presence of arg-pheamide at the C terminus (Fukusumi et al, 2006). GnIH homologs have been identified in other vertebrates from fish to humans (Tsutsui K and Ukena K, 2006; Ukena and Tsutsui, 2005; Zhang Y et al, 2010). All peptides ... ... ... ...
 
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Entry last modified: October 2020