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GRETA

[gene related to trichosanthin induced apoptosis] The gene fragment encoding this protein has been isolated from the leukemia cell line U937 undergoing cell death by apoptosis induced by a plant protein Trichosanthin. A segment of GRETA is 78.3 % homologous to BTK (Bruton's tyrosine kinase) at the nucleic acid level. mRNAs of various sizes exist and these transcripts are expressed differentially in untreated cells or cells treated with the plant protein.

For other entries pertaining to cell death mechanisms see also the Apoptosis and Cell Death Dictionary section of this encyclopedia.

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