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GLDC

(approved gene symbol) [Glycine decarboxylase]. This metabolic enzyme is known also as Glycine dehydrogenase and GCSP [glycine cleavage system P protein]. GLDC is a pyridoxal phosphate-dependent glycine decarboxylase, which is part of an enzyme system that catalyzes the degradation of glycine. The complex consists of P protein (EC1.4.4.2), which is GLDC, the T protein (EC2.1.2.10, aminomethyltransferase), the L protein (EC1.8.1.4, dihydrolipoyl dehydrogenase).

The cDNA has been cloned by Kume et al (1991), and the gene structure has been described by Takayanagi et al (2000).


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