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GCP-2

[Granulocyte chemotactic peptide-2, granulocyte chemoattractant protein-2] This factor of 6 kDa (75 amino acids) is produced by stimulated human osteosarcoma cells (MG-63). It is co-produced in minute amounts together with IL8. GCP-2 is structurally related to the other members of the IL8 family and belongs to the family of chemotactic cytokines known as Chemokines (CXC-Chemokines). A characteristic feature of this factor is the presence of a conserved ELR sequence motif.

The protein is known also as SCYB6 [small inducible cytokine subfamily B member 6] and the sequence is identical with that of murine ... ... ... ... ... Subscribe to continue reading! ... ...

 

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