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FDCPmix

(FDCP = factor-dependent cell progenitors) A multipotent cell line of hematopoietic stem cells obtained by long-term murine bone long-term BMC (bone marrow culture).

FDCPmix is able to differentiate along myeloid and erythroid lineages (see also: hematopoiesis) in response to specific cytokines. The cells then give rise to mixed colonies in a colony formation assay. These cells are thought to reflect closely the situation in vivo. They are used as a model for studying the control of growth and differentiation processes of multipotent hematopoietic stem cells and have been used as ... ... ... ... ... Subscribe to continue reading! ... ...

 

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