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EWI-2

[EWI motif-containing protein 2; glutamine-tryptophan-isoleucine-2] This protein copurifies with CD81 and forms complexes with CD81 and CD9 (Stipps et al, 2001). Schröder HM et al (2013) have reported interactions with the metalloproteinase MMP-14.

The protein is a member of the immunoglobulin superfamily and contains a Glu-Trp-Ile (EWI) motif not seen in other immunoglobulin proteins. The protein is expressed ubiquitously. The protein has been identified independently as KASP and PGRL.


Kolesnikova et al (2004) have reported that EWI-2 modulates functions of integrin-alpha-4 / integrin-beta-1 on ... ... ... ... ... Subscribe to continue reading! ... ...

 

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