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EL4

A murine T-lymphoma (thymoma) cell line established from a tumor induced by 9,10-dimethyl-1,2-benzanthracene in C57/BL/6N mice.

EL4 cells have been shown to secrete IL2, CSF, and MAF (macrophage activating factor) into the conditioned medium.

The cell line is used to assay IL1 (see also: bioassays, cytokine assays).

Many sublines of EL4 have been established but not all of them are responsive to IL1. The cells respond to IL1 isolated from almost all vertebrates. IL1 ... ... ... ... ... Subscribe to continue reading! ... ...

 

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