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EHZF

[Early hematopoietic zinc finger protein] The protein contains 30 copies of a zinc finger motif with 96 % homology to mouse Evi3, a gene associated with the retroviral integration site in AKXD-27 B-cell lymphomas. In sequence data banks the protein is known also as ZNF521 or Zfp521 [Zinc finger protein 521].


EHZF expression is abundant in human CD34(+) progenitor cells and declines rapidly during differentiation in response to cytokines. The majority of acute myelogenous leukemias express EHZF. In response to treatment with the ... ... ... ... ... Subscribe to continue reading! ... ...

 

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