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EGI

[epithelial cell-specific growth inhibitor; epithelial growth inhibitor] This protein of 27 kDa has been isolated from an acid-ethanol extract of human platelets (Huang et al, 1986, 1987). At doses lower than 40 pg/mL in medium containing 10 % fetal calf serum, EGI inhibits the growth of three non-malignant epithelial cell lines, BRL, MDCK (from Madin-Darby canine kidney) and BSC-1 (from African green monkey kidney). The protein appears to be identical with TGF-beta.

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