EDGF-2 |
edin |
Leukocyte chemotactic factor 2 amyloidosis |
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(approved gene symbol) [EGF-like repeats and discoidin I-like domains 3] Hidai et al (1998) have called the protein Del-1 [Developmental endothelial locus-1; Developmentally-regulated endothelial cell locus 1 protein].
The EDIL3 protein contains three EGF-like repeats homologous to those in Notch and related proteins, including an EGF-like repeat that contains an RGD motif, and two discoidin-1-like domains. EDIL3 is a glycoprotein secreted by endothelial cells in response to hypoxia or vascular inujury. The protein is found in association with the endothelial cell surface and the
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