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Defensin-beta-25

[Beta-defensin 25] In humans, this member of the Beta-defensins is being referred to as Defensin-beta-125 [Beta-defensin 125]; approved gene symbol: DEFB125. The exact function of this defensin is not known; it may play a role in innate immunity similar to other defensins. The mouse gene has been cloned by Hu et al (2014) who reported expression in the epididymis, where it is down-regulated by castration and dependent on testicular factors and not on androgens. The human gene (Rodríguez-Jiménez et al, 2003) is also expressed in the epididymis. Chen et al (2017) have reported enriched expression in ependymal cells ... ... ... ... ... Subscribe to continue reading! ... ...

 

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