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DTRAF1

DTRAF1, encoded by gene CG3048, is the Drosophila melanogaster homolog of TRAF1 [TNF receptor associated factor-1] (Zapata et al, 2000). DTRAF1 contains 7 zinc finger domains followed by a TRAF domain, similar to mammalian TRAF proteins and other members of this family identified in Caenorhabditis elegans, Arabidopsis, and Dictyostelium. Through its TRAF domain DTRAF1 binds to the p75 neurotrophin receptor and weakly to the LT-beta receptor. DTRAF1 can also self-associate and binds to human TRAF1, TRAF2, and TRAF4 ... ... ... ... ... Subscribe to continue reading! ... ...

 

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