DPP4

[dipeptidyl peptidase 4] In some references the enzyme is being referred to also as dipeptidyl aminopeptidase 4. In older references, the term X-PDAP [Xaa-Pro-dipeptidylaminopeptidase] or X-prolyl dipeptidyl aminopeptidase has been used but usually refers to enzymes with the same specificity found in microorganisms (see also: Kojima et al, 1980). DPP4 is a membrane glycoprotein serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptide chains. The cDNA has been cloned by Misumi et al (1992) and Tanaka et al (1992). Genomic organization, localization, and tissue expression have been reported by Abbot et al (1994).

DPP4 has been shown to be involved in ... ... ... ...
 
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Entry last modified: March 2017