DDX1

[DEAD box helicase 1; DEAD box protein 1; DEAD box 1; DEAD/H BOX 1] This protein contains a characteristic Asp-Glu-Ala-Asp (DEAD box) motif and is an RNA helicase. The cDNA has been cloned by Godbout and Squire (1993) as DBP-RB [DEAD box protein retinoblastoma], which is amplified in retinoblastoma cells.

DDX1 has been shown to associate with factors involved in 3' end cleavage and polyadenylation of pre-mRNAs (Bléoo et al, 2001).

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Entry last modified: April 2012