Cheesy necrosis |
chemerin-9 |
Familial exudative vitreoretinopathy |
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The approved gene symbol for chemerin is RARRES2 [retinoic acid receptor responder 2]. Nagpal S et al (1997) have identified Chemerin as TIG2 [tazarotene-induced gene-2].
Chemerin is a chemoattractant protein (see also: chemotaxis) structurally and evolutionary related to the cathelicidin precursors (antibacterial peptides), cystatin C and related peptides (cysteine protease inhibitors), and kininogens. The protein promotes calcium mobilization and chemotaxis of immature dendritic cells and macrophages but is not chemotactic for mature
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