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CTLL-2

A murine cytotoxic T-cell line derived from C57/Bl/6 inbred mice. The cells have been shown to secrete Serglycin into the conditioned medium.

CTLL-2 cells constitutively express IL2 receptors and depends entirely on the presence of IL2 for its growth (see also: Factor-dependent crll lines). It is used in bioassays of this factor (see also: cytokine assays). The cells appear to be capable of growing on a matrix containing immobilized IL2.

The activity of IL2 is determined by measuring the incorporation of tritiated thymidine into the newly synthesized DNA of the proliferating ... ... ... ... ... Subscribe to continue reading! ... ...

 

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