CH925
a human recombinant fusion protein consisting of IL6 and IL2 (see also: Muteins). CH925 possesses both IL2 and IL6 activities when assayed on CTLL-2 and 7TD1 cells, respectively (Zhao et al, 1994).
CH925 significantly augments growth of erythroid colony-forming units, CFU-E, and synergizes with erythropoietin and/or IL3 in a dose-dependent manner (Zhao et al, 1996). At a low dose CH925 causes active proliferation of LAK cells with an efficacy that is greater than that of IL2 and/or IL6.
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