CD317 |
CD319 |
ZDF rats |
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[CD318(+), CD318(-)]
Other designations:
CDCP1 [CUB domain containing protein 1]
SIMA135 [subtractive immunization M(+)HEp3 associated 135 kDa protein]
TRASK [transmembrane and associated with src kinases]
CD318 has been shown to be involved in cell adhesion, anchorage, and cell migration, in particular in various types of cancer cells where it plays a role in tumor progression and metastasis. These processes involve phosphorylation of the protein. It is also a marker for subsets of immature hematopoietic stem cells, is expressed in leukemic blasts, and appears to play a role in early erythropoiesis (see: CDCP1).
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