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[caspase recruitment domain-containing protein-10] This protein contains an N-terminal caspase recruitment domain (CARD). It also contains a C-terminal PDZ domain, an SH3 domain, and a GUK domain. CARD10 is expressed mainly in heart, kidney, and liver. CARD10 has been shown to activate transcription factor NF-kappa-B. The protein interacts with BCL10 but not with other proteins containing a CARD domain (Wang et al, 2001). The protein has been described as CARMA3 [CARD-MAGUK protein-3] by Gaide et al (2001). Mouse CARD10 has been identified by McAllister-Lucas et al (2001) as BIMP1
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