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BorfE2

This protein is encoded by open reading frame E2 of the bovine herpesvirus-4. Expression of the protein inhibits cell death by apoptosis induced by FAS antigen or TNF-alpha. The protein contains multiple copies of a death effector domain and interacts with caspase-8

For other entries pertaining to cell death mechanisms see also the Apoptosis and Cell Death Dictionary section of this encyclopedia. For other relevant entries see also the Pathogenicity/Virulence Factors Dictionary section of this encyclopedia.

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Entry last modified: June 2003

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