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BmDefensinA

[Bombyx mori defensin A] (MAHQRKSLVIFIFLTVLVFVFALPRDATVFDNQHSEVAIEKSTSKIDSS)

This defensin from the fat body of the silkworm, Bombyx mori is the ortholog of Spodoptera frugiperda Spodoptericin. BmDefensinA is expressed tissue-specifically in the fat body and is activated relatively weakly by bacteria such as Escherichia coli and Bacillus subtilis, and by an entomopathogenic fungus Beauveria bassiana (Kaneko et al, 2008). Wen et al (2009) have reported that this defensin is transcribed constitutively at a high level in the hemocyte, silk gland, head, and ovary of the silkworm larvae, and in the fat body of early-stage pupae and moth. Its expression is induced also strongly by immune challenge.

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