Bithorax

This Drosophila melanogaster protein is a member of a larger family of homeotic genes. Gene mutations show a phenotype resembling a duplication of the entire thorax (Bridges and Morgan, 1923). Bithorax is part of a large gene complex (termed the Bithorax complex, abbr. BX-C) (Martin et al, 1995) that controls the specification and development of the second thoracic segment, the abdomen, and the genital organs (Lewis, 1978; for overview see also: Maeda and Karch, 2010). Within this complex the three genes, transcription factor Ubx [ultrabithorax] (gene: CG10388) (for overview see: Tomoyasu et al, 2017; Diaz-de-la-Loza et al, 2020), transcription factor Abd-A [ ... ... ... ...
 
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Entry last modified: March 2020