Babo
[Drosophila baboon; Baboon] Babo is encoded by gene CG8224 in Drosophila melanogaster. It is being referred to also as Atr-I [Activin transmembrane receptor 1] (Wrana et al, 1994). Babo is a type I Activin receptor that exists in several splice variants (termed Babo(a), Babo(b), Babo(c)) expressed during development (Brummel et al, 1999; Jensen et al, 2009).
Babo signaling plays a role in regulating cell proliferation. In mammalian cells, activated Babo specifically stimulates SMAD2
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