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BROMO domain

[BROMO domains]

This sequence domain of approximately 110 amino acids was described for the first time by Tamkun et al (1992) in a Drosophila melanogaster gene (brahma) that regulates homeotic genes. The domain is found in a variety of DNA-binding proteins of mammalian, invertebrate and yeast origin. This includes chromatin-associated proteins such as histone acetylases and the ATPase component of certain nucleosome-remodeling complexes. The domain has been found in over 100 proteins and may occur as a single copy, or in duplicate. The domain may act as a protein-protein interaction motif ... ... ... ... ... Subscribe to continue reading! ... ...

 

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