Booroola fecundity gene |
border cells |
ADAM metallopeptidase with thrombospondin type 1 motif 14 |
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[Bone-derived osteoclast recruiting activity] This biochemically uncharacterized factor has been isolated from bovine bone. It copurifies with osteogenin but is not identical with osteogenin or TGF-beta. The factor promotes the formation of osteoclasts. BORA primarily causes the differentiation of osteoclast precursors and does not stimulate osteoclast function in vitro resorption assays with disaggregated rat osteoclasts.
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