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BMP15

[bone morphogenetic protein-15] BMP15 (125 amino acids) is a member of the family of bone morphogenetic proteins. It has been identified by Dube et al (1998) in the mouse and in humans. The gene maps to the X-chromosome in both species. The murine gene is expressed specifically in the oocyte. The murine protein is most closely related to murine GDF9. A previous designation for BMP15 is GDF9B [growth/differentiation factor-9B].

BMP15 is involved in the regulation of proliferation and differentiation of granulosa cells in the ovary, stimulating granulosa cell mitosis and inhibiting ... ... ... ... ... Subscribe to continue reading! ... ...

 

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