BMP15

[bone morphogenetic protein-15] BMP15 (125 amino acids) is a member of the family of bone morphogenetic proteins. It has been identified by Dube et al (1998) in the mouse and in humans. The gene maps to the X-chromosome in both species. The murine gene is expressed specifically in the oocyte. The murine protein is most closely related to murine GDF9. A previous designation for BMP15 is GDF9B [growth/differentiation factor-9B].

BMP15 is involved in the regulation of proliferation and differentiation of granulosa cells in the ovary, stimulating granulosa cell mitosis and inhibiting ... ... ... ...
 
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Entry last modified: January 2003