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[bone morphogenetic protein-10] BMP10 has been isolated from bovine sources. Bovine and human proteins are identical.
Murine BMP10 expression has been shown to be restricted to the developing heart. It may play a role in trabeculation of the embryonic heart (Neuhaus et al, 1999). See also: BMP (bone morphogenetic proteins). BMP10 signals through ACVRL1 [activin A receptor type II-like 1; activin A receptor type 2-like 1], a receptor expressed mainly on endothelial cells but also other cell types.
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