ATG7

[autophagy-related-7] This protein is known also as APG7L [APG7-like] (Yuan et al, 1999) or APG7 [Autophagy protein 7], which is the human homolog of yeast Apg7, a ubiquitin-activating enzyme E1-like protein essential for mediating membrane fusion in autophagy (Tanida et al, 2001); the protein is being referred to also as ubiquitin-activating enzyme E1-like protein. In Pichia pastoris, the same gene has been identified as GSA7 [glucose-induced selective autophagy 7] and has been shown to be involved in selective autophagy of peroxisomes (Yuan et al, 1999).

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Entry last modified: February 2008