AdIF |
ADIN |
NCK2 |
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[Autocrine differentiation-inhibiting factor] A biochemically uncharacterized factor found in the conditioned medium of tsAEV-LSCC HD3 chicken erythroid cells transformed by the avian erythroblastosis virus (Krsmanovic et al, 1988).
ADIF blocks the differentiation of the chicken erythroid cells that synthesize and secrete it into the conditioned medium without affecting proliferation (see also: autocrine). ADIF also prevents dimethylsulfoxide induced synthesis of hemoglobin by murine Friend erythroleukemia cells and also blocks erythroid differentiation in normal human
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