A-LAP

[adipocyte-derived leucine aminopeptidase] This widely expressed enzyme is a member of the M1 family of zinc metallopeptidases (Hattori et al (1999). It is known also as ARTS-1 [aminopeptidase regulator of TNFR1 shedding 1] (Cui et al, 2002), rat PILS-AP [puromycin-insensitive leucyl-specific aminopeptidase] (Schomburg et al, 2000), murine ERAAP [endoplasmic reticulum aminopeptidase associated with antigen processing] (Serwold et al, 2002), ERAP1 [endoplasmic reticulum aminopeptidase 1], KIAA0525 (Nagase et al, 1998)

The monomeric enzyme hydrolyzes a variety of bioactive ... ... ... ...
 
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Entry last modified: July 2022