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viprolaxikine

This is the term pertaining to a number of short anionic, antiviral peptides ultrafiltrates (5 kDa cutoff) of cell-free medium from mosquito cell cultures persistently infected with dengue virus DENV serotype 2 (DENV-2) (Laosutthipong et al, 2013).

Viprolaxikine reduces DENV-2 titers by almost 4 logs. Activity is highest against DENV-2, but there is also significant activity against the 3 other DENV serotypes. The peptides responsible for this activity have been identified as DDHELQD (Asp-Asp-His-Glu-Leu-Gln-Asp), DETELQD (Asp-Glu-Thr-Glu-Leu-Gln-Asp), DEVMLQD (Asp-Glu-Val-Met-Leu-Gln-Asp), DEVLMQD. (Asp-Glu-Val-Leu-Met-Gln-Asp ... ... ... ... ... Subscribe to continue reading! ... ...

 

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