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spitz

gene symbol: spi. The Drosophila melanogaster gene Spitz (CG10334) encodes a 26 kDa transmembrane structurally similar to TGF-alpha that is expressed throughout the embryo. Spitz is considered the Drosophila melanogaster homolog of TGF-alpha. For a homolog see also: Keren.

Spitz is involved in a number of unrelated developmental choices, for example, dorsal-ventral axis formation, glial migration, sensory organ determination, and muscle development (Rutledge et al, 1992).

Spitz binds to the Drosophila melanogaster EGF receptor, DER ... ... ... ... ... Subscribe to continue reading! ... ...

 

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