PALMD |
palmitate-induced cell death |
UCN2 neurons |
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approved gene symbol: PALMD. The gene is encoded by C1orf11 [chromosome 1 open reading frame 11]. Hu B et al (2001) have identified palmdelphin as a cytosolic protein related to Paralemmin-1, a protein implicated in plasma membrane dynamics, the development of filopodia, neurites and dendritic spines, as well as the invasiveness and metastatic potential of cancer cells.
The protein has been identified independently as PALML [paralemmin-like] by Andreu et al (2001), who reported expression in many tissues. Palmdelphin is most abundant in cardiac and skeletal muscle but absent from brain and blood. An exogenously expressed PALML
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